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AEDs could be used in the treatment of Alzheimer’s and Parkinson’s diseases, according to a study from Washington University in Missouri (United States) published in the journal Molecular Neurodegeneration.

Researchers have discovered a new mechanism of action of antiepileptic drugs to treat these neurodegenerative disorders. The study shows that neurons in the brain were getting protection after treatment with calcium channel blockers type T, that are commonly used to treat epilepsy.

The calcium signaling mechanisms play a key role in the survival of neurons in the brain. As age increases, you can alter calcium homeostasis in the brain, leading to cognitive and functional decline. This thereby increases the likelihood that chemical compounds capable of modulating calcium homeostasis can protect neurons.

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